Stefan Lethagen Selected Research

Type 1 von Willebrand Disease

8/2018	Genetic Variation in the Syntaxin-Binding Protein STXBP5 in Type 1 von Willebrand Disease Patients.
1/2018	Genetic variation in the C-type lectin receptor CLEC4M in type 1 von Willebrand Disease patients.
1/2018	Genetic Variation in the von Willebrand Factor Gene in Swedish von Willebrand Disease Patients.
1/2015	Identification and Characterization of Novel Variations in Platelet G-Protein Coupled Receptor (GPCR) Genes in Patients Historically Diagnosed with Type 1 von Willebrand Disease.
7/2011	Variation in the VWF gene in Swedish patients with type 1 von Willebrand Disease.
11/2010	The impact of bleeding history, von Willebrand factor and PFA-100(®) on the diagnosis of type 1 von Willebrand disease: results from the European study MCMDM-1VWD.
5/2008	Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: molecular and clinical markers for the diagnosis and management of type 1 VWD (MCMDM-1VWD).
4/2008	Response to desmopressin is influenced by the genotype and phenotype in type 1 von Willebrand disease (VWD): results from the European Study MCMDM-1VWD.
1/2007	Phenotype and genotype of a cohort of families historically diagnosed with type 1 von Willebrand disease in the European study, Molecular and Clinical Markers for the Diagnosis and Management of Type 1 von Willebrand Disease (MCMDM-1VWD).

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Stefan Lethagen Research Topics

Disease

16	Hemorrhage 01/2021 - 02/2003
9	Type 1 von Willebrand Disease 08/2018 - 01/2007
8	Hemophilia A (Haemophilia) 01/2022 - 02/2003
7	von Willebrand Diseases (von Willebrand's Disease) 10/2020 - 09/2002
3	Hemophilia B (Haemophilia B) 09/2021 - 04/2017
2	Body Weight (Weight, Body) 06/2005 - 03/2003
1	Nephrosis 09/2021
1	Thrombocytopenia (Thrombopenia) 02/2009
1	MYH9-Related Disorders 03/2008
1	Epistaxis (Nosebleed) 08/2007
1	Hematuria 08/2007
1	Hypoprothrombinemias (Prothrombin Deficiency) 01/2006
1	Joint Diseases (Joint Disease) 01/2006
1	Critical Illness (Critically Ill) 01/2005
1	Chronic Kidney Failure (Chronic Renal Failure) 03/2003
1	Renal Insufficiency (Renal Failure) 03/2003
1	Communicable Diseases (Infectious Diseases) 02/2003
1	Ischemic Stroke 01/2003
1	Stroke (Strokes) 01/2003

Drug/Important Bio-Agent (IBA)

13	von Willebrand FactorIBA 10/2020 - 09/2002
8	Factor VIII (Coagulation Factor VIII)IBA 01/2022 - 01/2006
4	Biomarkers (Surrogate Marker)IBA 11/2010 - 01/2007
4	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 05/2008 - 02/2003
3	recombinant FVIIa (rFVIIa)FDA Link 08/2010 - 06/2005
2	emicizumabIBA 01/2021 - 01/2020
1	Nonsense Codon (Nonsense Mutation)IBA 09/2021
1	factor VIII-Fc fusion proteinIBA 01/2021
1	factor IX Fc fusion proteinIBA 01/2019
1	Carrier Proteins (Binding Protein)IBA 08/2018
1	Qa-SNARE Proteins (Syntaxin)IBA 08/2018
1	Blood Coagulation Factors (Coagulation Factor)IBA 07/2018
1	C-Type Lectins (C-Type Lectin)IBA 01/2018
1	Purinergic P2 Receptors (ADP Receptor)IBA 01/2015
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2015
1	NucleotidesIBA 01/2015
1	Thromboplastin (Tissue Factor)IBA 08/2010
1	Tissue Plasminogen Activator (Alteplase)FDA Link 08/2010
1	KaolinIBA 08/2010
1	InnovinIBA 08/2010
1	Heparin (Liquaemin)FDA LinkGeneric 02/2009
1	ABO Blood-Group SystemIBA 06/2008
1	Arginine Vasopressin (Argipressin)IBA 05/2008
1	von Willebrand factor drug combination factor VIIIIBA 05/2008
1	Biological ProductsIBA 04/2008
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 03/2008
1	Nonmuscle Myosin Type IIAIBA 03/2008
1	Prothrombin (Factor II)IBA 01/2006
1	Fibrinogen (Factor I)FDA Link 06/2005
1	Protein CIBA 01/2005
1	Antidiuretic AgentsIBA 03/2003
1	ElectrolytesIBA 03/2003
1	CreatinineIBA 03/2003
1	Hemostatics (Antihemorrhagics)IBA 02/2003
1	Pharmaceutical PreparationsIBA 02/2003
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2003
1	Cyclooxygenase 1IBA 01/2003
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2003

Therapy/Procedure

4	Therapeutics 09/2021 - 02/2003
1	Injections 04/2017
1	Tooth Extraction (Tooth Extractions) 08/2007